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While Set himself is not present, his lieutenant, Grog the God-Killer is, as is the massive serpentine Apep. With the meeting done, Black Bolt moves to engage Grog - given that the God-Killer has held his own with Thor in the past, no one else in the field comes close to being able to hold him off.
The rest of the Legion, aside from Apep, are not so potent, but they are numerous. Natasha's armor proves quite effective at turning away the worst of their blasts, protecting her from their mystical poisons. They're far tougher than humans, but still get scattered by her repulsors and upgraded Widow's Bites.